GHK-CU

GHK-Cu is a naturally occurring tripeptide-copper complex, originally isolated from human plasma. Circulating levels decline with age—from ~200 ng/mL at age 20 to ~80 ng/mL by age 60—correlating with decreased regenerative capacity.

Enhanced Wound Healing: 64.5% reduction in wound size versus controls.
Skin Rejuvenation: 55.8% clinical reduction in wrinkle volume.
Collagen Synthesis: Stimulates at nanomolar concentrations in fibroblasts.
Antioxidant Activity: Superior hydroxyl radical scavenging compared to glutathione.
DNA Repair: Upregulates 47 genes involved in DNA repair.
Anti-inflammatory: Reduces TNF-α-induced IL-6 secretion in fibroblasts.
Cognitive Support: Improves spatial navigation in aged murine models.
Systemic Tissue Regeneration: Benefits reported across multiple organ systems.

Pickart L, Vasquez-Soltero JM, Margolina A. Regenerative and protective actions of GHK-Cu peptide in light of new gene data. Int J Mol Sci. 2018;19(7):1987. DOI
Pickart L, Vasquez-Soltero JM, Margolina A. GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed Res Int. 2015;2015:648108. DOI
Abdulghani AA, et al. Effects of topical creams containing vitamin C, copper-binding peptide, and melatonin vs tretinoin on normal skin. Dis Manag Clin Outcomes. 1998;1(4):136-141.
Dou Y, Lee A, Zhu L, Morton J, Ladiges W. The potential of GHK as an anti-aging peptide. Aging Pathobiol Ther. 2020;2(1):1-5. DOI
Pickart L, Margolina A. Effect of GHK-Cu on stem cell actions and gene expression. OBM Geriatrics. 2018;2(3):009. DOI

$66.00

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