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IGF-1LR3
IGF-1LR3

IGF-1LR3

IGF-1 LR3 is a synthetic analog of IGF-1, engineered with:

  • Arginine substitution at position 3 (Arg3)
  • Extended peptide sequence

These modifications

  • Increase stability and half-life
  • Enhance IGF-1 receptor binding affinity
  • Amplify anabolic potency compared to native IGF-1
  • Muscle Growth: Increases lean body mass viasatellite cell proliferation and differentiation
  • Recovery & Regeneration: Accelerates repair ofskeletal muscle, tendons, ligaments, and other tissues post-injury or exercise
  • Protein Synthesis: Enhances anabolic processesfor faster muscle development
  • Fat Metabolism: Improves glucose utilization and promotes fat oxidation
  • Insulin Sensitivity: Enhances insulin action andglucose uptake in tissues
  • Bone Health: Supports bone density and skeletaltissue strength
  • Cardiovascular Health: Promotes angiogenesis and endothelial function, aiding vascular repair
  1. Frost RA, Lang CH. Regulation of insulin-like growth factor-1 expression and its role in thegrowth of skeletal muscle. Growth Horm IGF Res. 2007;17(5):311-322.
  2. Barton-Davis ER, et al. IGF-1 LR3 increases muscle mass and strength in mice. J ClinInvest. 1999;103(2):299-306.
  3. Roh JD, et al. Insulin-like growth factor-1 (IGF-1) promotes vascular repair and improvesendothelial function in aging. Mol Ther. 2009;17(9):1679-1685.
  4. Clemmons DR. Role of IGF-1 in the management of growth and metabolism. J ClinEndocrinol Metab. 2007;92(4):1419-1427.

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