MGF

MGF is a splice variant of IGF-1 (IGF-1Ec), released locally in skeletal muscle and other tissues in response to mechanical stress or injury.

Muscle Regeneration: Accelerates repair via satellite cell activation
Muscle Mass & Strength: Enhances hypertrophy and post-exercise strength
Sarcopenia Mitigation: Preserves muscle tissue in aging populations
Bone Healing: Speeds fracture repair and osteoblast proliferation
Cartilage Protection: Reduces osteoarthritis progression
Cardiac Preservation: Limits myocardial damage after infarction
Neurogenesis: Stimulates neural stem cell proliferation in aging brains
Muscle Disease Repair: Supports regeneration in conditions like ALS
Localized Action: Minimal systemic side effects due to tissue-specific release
Wound Healing: Enhances tissue repair and cellular proliferation

Ates, K., et al. (2007). “The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle.” FEBS Letters, 581(14), 2727–2732. DOI
Kandalla, P.K., et al. (2011). “Mechano Growth Factor E peptide (MGF-E) activates human muscle progenitor cells and increases their fusion potential at different ages.” Mechanisms of Ageing and Development, 132(4), 154–162. DOI
Deng, M., et al. (2011). “Mechano growth factor E peptide promotes osteoblast proliferation and bone-defect healing in rabbits.” International Orthopaedics, 35(7), 1099–1106. DOI
Tang, J.J., et al. (2017). “Mechano growth factor promotes neurogenesis in the aging mouse brain.” Molecular Brain, 10(1), 23. DOI
Carpenter, V., et al. (2008). “Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction.” Heart, Lung and Circulation, 17(1), 33–39. DOI

$75.00

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