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Oxytocin

Oxytocin is a nonapeptide neurohormone synthesized in the hypothalamus and released by the posterior pituitary gland. While classically known for its roles in reproduction, it functions broadly as a multifunctional neuropeptide across the central nervous system and periphery.

Pain Reduction: Used clinically for labor induction and lactation support
Social Behavior: Enhances prosocial behavior and eye contact in autism spectrum disorder (Andari et al., 2010)
Anxiety & Mood: Reduces cortisol, activates GABAergic pathways, potential antidepressant effects (Goodin et al., 2015)
Reproductive Health: FDA-approved for uterine contractions; promotes milk ejection and mother-infant bonding
Anti-inflammatory: Reduces cytokines and oxidative stress
Metabolic & Cardiovascular: Improves glucose metabolism and insulin sensitivity (Lawson et al., 2024)

Approved uses: Labor induction, uterine contraction, and lactation support.
Investigational Uses: Pain management, autism therapy, metabolic modulation, anxiety, and mood disorders.
Delivery Preference: Intranasal administration is non-invasive and effective for CNS-targeted studies.

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