Selank

Selank (Elank) is a synthetic heptapeptide modeled after tuftsin, an endogenous immunomodulatory peptide. It is frequently used in research investigating central nervous system signaling, neurotransmitter pathways, and interactions between neuropeptides and immune regulation.

Selank’s structure and pathway interactions make it a tool for studying mechanisms related to serotonergic signaling, GABAergic modulation, peptide-based immunomodulation, and neurotrophic pathway activity.

Mechanisms of Action
(Based on published scientific literature — not effects of this product.)

  • Neurotransmitter Pathway Interaction:
Selank has been studied for its ability to influence serotonergic and GABAergic systems, providing a model for exploring neurochemical balance and CNS signaling.
  • Neuropeptide Modulation:
Research indicates involvement in pathways associated with learning, memory, and cognitive processing through interaction with neurotrophic systems.
  • Stress-Response Pathways:
Literature suggests Selank may influence CNS responses related to stress signaling, neuronal excitability, and oxidative stress models.
  • Immunomodulatory Effects:
Tuftsin-derived peptides, including Selank, have been studied for their ability to modulate adaptive immune pathways and inflammatory responses.

Clinical References

  1. Mikulevsky, M., et al. (2014). Effects of Selank on memory, learning, and mood in animals and humans.
  2. Rogozin, M. P., et al. (2005). Selank: A neuropeptide with anxiolytic and neuroprotective properties.
  3. Tse, A. B., et al. (2020). Evaluation of Selank’s effects on stress and mood regulation.

*These findings summarize published scientific research and do not represent the effects of this laboratory-use material. Not FDA-approved. Not for clinical, diagnostic, or therapeutic use.

  • Behavioral Neuroscience Models: Selank has been investigated in animal and human research models for its influence on behavioral and cognitive performance.
  • Neurochemical Homeostasis: Literature explores how Selank may affect neurotransmitter turnover, receptor activity patterns, and neurochemical stability.
  • CNS Stress Pathway Studies: Several publications examine Selank’s role in models of stress responsiveness and neural adaptation.
  • Neuroprotection Research: Studies evaluate Selank’s potential involvement in oxidative-stress pathways, neuronal resilience, and excitotoxicity models.
  • Immune-CNS Interaction: Selank is commonly used to explore connections between immune peptides and central nervous system regulation.

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