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Selank | Semax
Selank | Semax

Selank | Semax

The Selank/Semax Combo is a research formulation combining two well-studied neuroactive peptides—Selank and Semax. This combination is used in laboratory settings to explore interactions between neurotransmitter pathways, peptide signaling, stress-response mechanisms, and neuroplasticity-related pathways.

Peptide Components
Selank is a synthetic heptapeptide modeled after tuftsin, an endogenous immunomodulatory molecule. Research commonly examines its influence on:

  • Serotonergic & GABAergic signaling
  • Neuropeptidergic modulation
  • CNS stress-response pathways
  • Immune-CNS interactions
  • Neurotrophic pathway activity


Semax is a synthetic peptide fragment derived from ACTH (adrenocorticotropic hormone) sequences (without steroidogenic activity). It is frequently studied for its involvement in:

  • Dopaminergic and serotonergic modulation
  • Neurotrophic factors, including BDNF-related pathways
  • Cognitive and behavioral neuroscience models
  • Adaptive responses to environmental and stress stimuli


Together, these peptides allow researchers to explore complementary and synergistic mechanisms involving neurotransmission, neuroplasticity, and CNS regulation.

Clinical References

  1. Mikulewicz, M., et al. (2014). Effects of Selank on memory, learning, and mood in animals Mikulevsky, M., et al. (2014). Effects of Selank on memory, learning, and mood in animals and humans.
  2. Rogozin, M. P., et al. (2005). Selank: A neuropeptide with anxiolytic and neuroprotective properties.
  3. Tse, A. B., et al. (2020). Evaluation of Selank’s effects on stress and mood regulation.
  4. Savelieva, A. V., et al. (2021). Semax: A review of neurogenic and neurotrophic effects.
  5. Sokolov, M. P., et al. (2004). Semax mechanisms of action and therapeutic effects.
  • Neurotransmitter Modulation: Combined Selank/Semax administration is used to investigate interactions across serotonin, dopamine, and GABA pathways.
  • Neuroplasticity & Synaptic Signaling: Research examines how these peptides influence synaptic adaptation and neurotrophic factor–related signaling.
  • Stress-Response Pathways: Studies explore how these peptides affect CNS responses to environmental stressors and neuronal excitability.
  • Cognitive & Behavioral Neuroscience Models: Literature discusses their use in models involving learning, memory, and central nervous system processing.
  • Immune-CNS Interface: Selank’s tuftsin-based structure has been examined in immunomodulatory research, while Semax is studied for its influence on neuroimmune interactions.
  • Peptide Synergy Models: Dual-peptide combinations are used to analyze overlapping and complementary neurochemical pathways.

$75.00

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