Semax

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH 4-10 fragment and modified with a stabilizing C-terminal Pro-Gly-Pro sequence. Originally developed in Russia, Semax is a nootropic and neuroprotective peptide with pronounced effects on cognition, neuroplasticity, and stress resilience, without influencing systemic cortisol levels.

Cognitive Enhancement: Improves memory, attention, learning, and mental clarity
Neuroprotection: Protects neurons from ischemia, excitotoxicity, and neurodegeneration
Stress Resilience: Produces anxiolytic and antidepressant-like effects
Recovery Support: Accelerates post-stroke and post-injury brain repair
Immune Support: Modulates immune activity in brain tissue, reducing inflammation
Metal Toxicity Protection: Decreases neurotoxic effects from heavy metals
Brain Circulation: Enhances microcirculation and oxygen delivery to neural tissue

Medvedeva, E.V., et al. (2014). The peptide Semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. BMC Genomics, 15, 228. DOI: 10.1186/1471-2164-15-228.
Dolotov, O.V., et al. (2006). Semax increases brain-derived neurotrophic factor protein in rat basal forebrain. Journal of Neurochemistry, 97(Suppl 1), 82-86. DOI: 10.1111/j.1471-4159.2006.03658.x.
Sudarkina, O.Y., et al. (2021). Protective effect of Semax in cerebral ischemia-reperfusion. Int. J. Mol. Sci., 22(12), 6179. DOI: 10.3390/ijms22126179.
Levitskaya, N.G., et al. (2004). Neuroprotective effects of Semax in MPTP-induced lesions. Neurosci. Behav. Physiol., 34(4), 399-405. DOI: 10.1023/b:neab.0000018752.59465.28.
Tabbi, G., et al. (2015). Semax protects against metal-induced toxicity. J. Inorg. Biochem., 142, 1-4. DOI: 10.1016/j.jinorgbio.2014.09.016.

$38.00

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