Thymalin

Thymalin is a polypeptide bioregulator derived from thymus-associated peptide fragments.
It is composed of a mixture of short peptides such as EW (Glu-Trp), KE (Lys-Glu), and EDP (Glu-Asp-Pro), which have been studied for their role in supporting gene-regulatory processes and cellular homeostasis.
Research suggests that thymus-derived peptide complexes may influence cellular signaling related to immune system activity, tissue maintenance, and adaptive stress responses. Thymalin is provided strictly for laboratory research use and is not approved for human or veterinary applications.

  • Epigenetic Modulation
Thymus-derived peptides may interact with chromosomal proteins and histones to influence gene-expression activity.
  • Peptide-Cell Communication
Investigated for its role in supporting cellular signaling pathways involved in immune system coordination.
  • Protein Synthesis Support
Research suggests bioregulatory influence on pathways associated with structural protein synthesis.
  • Stress-Response Modulation
Preclinical data show potential interaction with cytokine-related signaling pathways.

Clinical References

  1. Khavinson, V.Kh., et al. (2021). The use of Thymalin for immunocorrection and molecular aspects of biological activity. Biology Bulletin Reviews, 11(4), 377–382. DOI: 10.1134/S2079086421040046
  2. Kuznik, B.I., et al. (2021). Peptide drug Thymalin regulates immune status in severe COVID-19 older patients. Advances in Gerontology, 11(4), 368–376. DOI: 10.1134/S2079057021040068
  3. Khavinson, V.Kh., et al. (2020). Thymalin: activation of differentiation of human hematopoietic stem cells. Bulletin of Experimental Biology and Medicine, 170(1), 118–122. DOI: 10.1007/s10517-020-05016-z
  4. Anisimov, V.N., et al. (2010). Peptide bioregulation of aging: results and prospects. Biogerontology, 11(2), 139–149. DOI: 10.1007/s10522-009-9249-8
  5. Khavinson, V.Kh., et al. (2013). Peptide bioregulators: a new class of geroprotectors. Advances in Gerontology, 3(3), 225–235. DOI: 10.1134/S2079057013030065

*Based on published research. Not intended to imply human outcomes.

  • Immune Cell Signaling Support: Research indicates thymus-derived peptides may support signaling pathways related to T-cell activity and immune system communication. (Preclinical/Human literature — non-disease specific)
  • Cellular Regulation: Studies show modulation of gene-expression markers involved in cellular differentiation, stress response, and tissue recovery. (Preclinical Research)
  • Homeostatic Balance: Literature suggests improved regulation of certain biomarkers associated with cellular equilibrium and metabolic stability. (Preclinical Research)
  • Adaptive Stress Response: Investigated for potential support of cellular resilience during periods of physiological stress. (Preclinical Research)
  • Hematopoietic Support Signals: Some studies note modulation of markers associated with red and white blood cell formation. (Preclinical Research)
  • Age-Related Cellular Pathways: Exploratory research examines its role in supporting normal age-related cellular changes, without claiming therapeutic benefit. (Preclinical Research)

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